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Information About Psychtropic Drugs

What is Prozac?

GENERIC NAME: Fluoxetine
BRAND NAMES: Prozac, Prozac Weekly, Rapiflux, Sarafem




PROZAC is a chemical substance that crosses the blood-brain barrier and acts primarily upon the central nervous system where it affects brain function, resulting in changes in perception, mood, consciousness, cognition, and behavior. Prozac also produces a range of physical side effects, as well as undesirable mental and physical manifestations when being discontinued. Because of these, Prozac can be addictive. For information on how to to safely break the dependency on Prozac or discontinue it under medical supervision, click here. For information on your rights if you or a family member is being urged to take Prozac, click here.

PROZAC SIDE EFFECT: Aggravated nervousness

A progressively worsening, irritated and troubled state of mind.

Suddenly violent and forceful, emotionally disturbed state of mind.


Long term or short term, partial or full memory loss created by emotional or physical shock, severe illness, or a blow to the head where the person was caused pain and became unconsciousness.

PROZAC SIDE EFFECT: Anxiety attack

Sudden and intense feelings of fear, terror, and dread physically creating shortness of breath, sweating, trembling and heart palpitations.


Complete lack of concern or interest for things that ordinarily would be regarded as important or would normally cause concern.

PROZAC SIDE EFFECT: Appetite decreased

Having a lack of appetite despite the ordinary caloric demands of living with a resulting unintentional loss of weight.

PROZAC SIDE EFFECT: Appetite increased

An unusual hunger causing one to overeat.

PROZAC SIDE EFFECT: Auditory hallucination

Hearing things without the voices or noises being present.


Grinding and clenching of teeth while sleeping.

PROZAC SIDE EFFECT: Carbohydrate craving

An urge and craving to eat foods rich in sugar and starches (sweets, snacks and junk foods) that intensifies as the diet becomes more and more unbalanced due to the unbalancing of the proper nutritional requirements of the body.

PROZAC SIDE EFFECT: Concentration impaired

Unable to easily focus your attention for long periods of time.

Not able to think clearly and understand in order to make a logical decision.

PROZAC SIDE EFFECT: Crying, abnormal

Unusual and not normal fits of weeping for short or long periods of time for no apparent reason.

PROZAC SIDE EFFECT: Depersonalization

A condition where one has lost a normal sense of personal identity.

A hopeless feeling of failure, loss and sadness that can deteriorate into thoughts of death.

PROZAC SIDE EFFECT: Disorientation

A loss of sense of direction, place, time or surroundings as well as mental confusion on personal identity.

PROZAC SIDE EFFECT: Dreaming, abnormal

Dreaming that leaves a very clear, detailed picture and impression when awake that can last for a long period of time and sometimes be unpleasant.

PROZAC SIDE EFFECT: Emotional lability

Suddenly breaking out in laughter or crying or doing both without being able to control the outburst of emotion. These episodes are unstable as they are caused by things that normally would not have this effect on an individual.


Uncontrollably responding to stimuli.

PROZAC SIDE EFFECT: Feeling unreal

The awareness that one has an undesirable emotion like fear but can’t seem to shake off the irrational feeling. For example, feeling like one is going crazy but rationally knowing that it is not true. The quality of this side effect resembles being in a bad dream and not being able to wake up.


Unable to remember what one ordinarily would remember.


Sleeplessness caused by physical stress, mental stress or stimulants such as coffee or medications; it is a condition of being abnormally awake when one would ordinarily be able to fall and remain asleep.


Abnormally annoyed in response to a stimulus.


Nervous fidgeting without an apparent cause.

Mental and physical sluggishness and apathy that can deteriorate into an unconscious state resembling deep sleep. A numbed state of mind.

PROZAC SIDE EFFECT: Libido decreased

An abnormal loss of sexual energy or desire.

PROZAC SIDE EFFECT: Panic reaction

A sudden, overpowering, chaotic and confused mental state of terror resulting in being doubt ridden often accompanied with hyperventilation, and extreme anxiety.

PROZAC SIDE EFFECT: Restlessness, aggravated

A constantly worsening troubled state of mind characterized by the person being increasingly nervous, unable to relax, and easily angered.


Feeling sleepy all the time or having a condition of semi-consciousness.

PROZAC SIDE EFFECT: Suicide attempt

An unsuccessful deliberate attack on one’s own life with the intention of ending it.

PROZAC SIDE EFFECT: Suicidal tendency

Most likely will attempt to kill oneself.

PROZAC SIDE EFFECT: Tremulousness, Nervous

Very jumpy, shaky, and uneasy while feeling fearful and timid. The condition is characterized by thoughts of dreading the future, involuntary quivering, trembling, and feeling distressed and suddenly upset.


PROZAC SIDE EFFECT: Carpal tunnel syndrome

A pinched nerve in the wrist that causes pain, tingling, and numbing.

PROZAC SIDE EFFECT: Coordination, abnormal

A lack of normal, harmonious interaction of the parts of the body when it is in motion.


Losing one’s balance while feeling unsteady and lightheaded which may lead to fainting.

PROZAC SIDE EFFECT: Disequilibrium

Lack of mental and emotional balance.


A temporary condition where one is likely to go unconscious and fall.

A sharp or dull persistent pain in the head

Prozac side effect: Hyperreflexia

A not normal and involuntary increased response in the tissues connecting the bones to the muscles.

PROZAC SIDE EFFECT: Light-headed feeling

Uncontrolled and usually brief loss of consciousness caused by lack of oxygen to the brain.


Reoccurring severe head pain usually with nausea, vomiting, dizziness, flashes or spots before the eyes, and ringing in the ears

PROZAC SIDE EFFECT: Muscle contractions, involuntary

Spontaneous and uncontrollable tightening reaction of the muscles caused by electrical impulses from the nervous system.
PROZAC SIDE EFFECT: Muscular tone, increased

Uncontrolled and exaggeration muscle tension. Muscles are normally partially tensed and this is what gives us muscle tone.


Burning, prickly, itchy, or tingling skin with no obvious or understood physical cause.


A need to move the legs without any apparent reason. Sometimes there is pain, twitching, jerking, cramping, burning, or a creepy-crawly sensation associated with the movements. It worsens when a person is inactive and can interrupt one’s sleep so one feels the need to move to gain some relief.

Uncontrolled quivering and trembling as if one is cold and chilled.


Lack of alertness and energy, as well as being slow to respond or perform in life.


A contraction of a muscle causing a repeated movement not under the control of the person usually on the face or limbs.


A nervous and involuntary vibrating or quivering of the body.


Sharp, jerky and spastic motion sometimes with a sharp sudden pain.

A sensation of dizziness with disorientation and confusion.



The extreme sensitivity of body tissues triggered by substances in the air, drugs, or foods causing a reaction like sneezing, itching, asthma, hay fever, skin rashes, nausea and/or vomiting.


A violent, sudden, and severe drop in blood pressure caused by a re-exposure to a foreign protein or a second dosage of a drug that may be fatal unless emergency treatment is given right away.

A physically weak condition.


Severe discomfort in the chest caused by not enough oxygen going to the heart because of narrowing of the blood vessels or spasms.


Appearing pale while cold and shivering; sometimes with a fever.


The usual amount to moisture in the mouth is noticeably less.

PROZAC SIDE EFFECT: Edema of extremities

Abnormal swelling of the body’s tissue caused by the collection of fluid.


To suddenly lose your normal standing upright position as if you were shot.


Loss of normal strength so as to not be able to do the usual physical and mental activities.

Prozac side effect: Fever

Abnormally high body temperature, the normal being 98 degrees Fahrenheit or 37 degrees Centigrade in humans, which is a symptom of disease or disorder in the body. The body is affected by feeling hot, chilled, sweaty, weak and exhausted. If the fever goes too high, death can result.


Brief, abnormal enlargement of the blood vessels that causes a sudden heat sensation over the entire body. Women in menopause will sometimes experience this.

PROZAC SIDE EFFECT: Influenza-like symptoms

Demonstrating irritation of the respiratory tract (organs of breathing) such as a cold, sudden fever, aches and pains, as well as feeling weak and seeking bed rest, which is similar to having the flu.


A hurtful sensation in the legs that is caused by excessive stimulation of the nerve endings in the legs and results in extreme discomfort.


The somewhat unclear feeling of discomfort you get when you start to feel sick.


Sudden, sharp and uncontrolled leg discomfort.


A short period of light headedness or unconsciousness (black-out) also know as fainting caused by lack of oxygen to the brain because of an interruption in blood flowing to the brain.

PROZAC SIDE EFFECT: Sweating increased

A large quantity of perspiration that is medically caused.

PROZAC SIDE EFFECT: Tightness of Chest

Mild or sharp discomfort, tightness or pressure in the chest area (anywhere between the throat and belly). The causes can be mild or seriously life-threatening because they include the heart, lungs and surrounding muscles.


Involuntary opening of the mouth with deep inhalation of air.


PROZAC SIDE EFFECT: Reproductive disorder, Female

Inability of a woman to conceive.

PROZAC SIDE EFFECT: Breast neoplasm

A tumor or cancer, of either of the two milk-secreting organs on the chest of a woman.


Abnormally heavy menstrual period or a menstrual flow that has continued for an unusually long period of time.

PROZAC SIDE EFFECT: Menstrual cramps

Painful, involuntary uterus contractions that women experience around the time of their menstrual period, sometimes causing pain in the lower back and thighs.

PROZAC SIDE EFFECT: Menstrual disorder

A disturbance or derangement in the normal function of a woman’s menstrual period.

PROZAC SIDE EFFECT: Pelvic Inflammation

The reaction of the body to infectious, allergic, or chemical irritation, which in turn causes tissue irritation, injury, or bacterial infection characterized by pain, redness, swelling, and sometimes loss of function. The reaction usually begins in the uterus and spreads to the fallopian tubes, ovaries, and other areas in the hipbone region of the body.

PROZAC SIDE EFFECT: Premenstrual syndrome

Various physical and mental symptoms commonly experienced by women of childbearing age usually 2 to 7 days before the start of their monthly period. There are over 150 symptoms including eating binges, behavioral changes, moodiness, irritability, fatigue, fluid retention, breast tenderness, headaches, bloating, anxiety, and depression. The symptoms cease shortly after the period begins, and disappear with menopause.

PROZAC SIDE EFFECT: Spotting between menses

Abnormal bleeding between periods. Unusual spotting between menstrual cycles.



Prozac side effect: Palpitation

Unusual and not normal heartbeat, that is sometimes irregular, but rapid and forceful thumping or fluttering. It can be brought on by shock, excitement, exertion, or medical stimulants. A person is normally unaware of his/her heartbeat.

Prozac side effect: Hypertension

High blood pressure, which is a symptom of disease in the blood vessels leading away from the heart. Hypertension is known as the “silent killer”. The symptoms are usually not obvious, however it can lead to damage to the heart, brain, kidneys and eye, and even to stroke and kidney failure. Treatment includes dietary and lifestyle changes.

Prozac side effect: Bradycardia

The heart rate is slowed from 72 beats per minute, which is normal, to below 60 beats per minute in an adult.

Prozac side effect: Tachycardia

The heart rate is speeded up to above 100 beats per minute in an adult. Normal adult heart rate is 72 beats per minute.

Prozac side effect: Abnormal ECG

A test called an electrocardiogram (ECG) that records the activity of the heart. It measures heartbeats as will as the position and size of the heart’s four chambers. It also measures if there is damage to the heart and the effects of drugs or mechanical devices like a pacemaker on the heart. When the test is abnormal this means that one or more of the following are present: heart disease, defects, beating too fast or too slow, disease of the blood vessels leading from the heart or of the heart valves, and/or a past or about to occur heart attack.

Prozac side effect: Flushing

The skin all over the body turns red.

Prozac side effect: Varicose vein

Unusually swollen veins near the surface of the skin that sometimes appear twisted and knotted, but always enlarged. They are called hemorrhoids when they appear around the rectum. The cause is attributed to hereditary weakness in the veins aggravated by obesity, pregnancy, pressure from standing, aging, etc. Severe cases may develop swelling in the legs, ankles and feet, eczema and/or ulcers in the affected areas.



Prozac side effect: Abdominal cramp/pain

Sudden, severe, uncontrollable and painful shortening and thickening of the muscles in the belly. The belly includes the stomach as well as the intestines, liver, kidneys, pancreas, spleen, gall bladder, and urinary bladder.

Prozac side effect: Belching

Noisy release of gas from the stomach through the mouth; a burp.

Prozac side effect: Bloating

Swelling of the belly caused by excessive intestinal gas.

Prozac side effect: Constipation

Difficulty in having a bowel movement where the material in the bowels is hard due to a lack of exercise, fluid intake, and roughage in the diet, or due to certain drugs.

Prozac side effect: Diarrhea

Unusually frequent and excessive, runny bowel movements that may result in severe dehydration and shock.

Prozac side effect: Dyspepsia

Indigestion. This is the discomfort you experience after eating. It can be heartburn, gas, nausea, a bellyache or bloating.

Prozac side effect: Flatulence

More gas than normal in the digestive organs.

Prozac side effect: Gagging

Involuntary choking and/or involuntary throwing up.

Prozac side effect: Gastritis

A severe irritation of the mucus lining of the stomach either short in duration or lasting for a long period of time.
Prozac side effect: Gastroenteritis

A condition where the membranes of the stomach and intestines are irritated.
Prozac side effect: Gastroesophageal Reflux

A continuous state where stomach juices flow back into the throat causing acid indigestion and heartburn and possibly injury to the throat.

Prozac side effect: Heartburn

A burning pain in the area of the breastbone caused by stomach juices flowing back up into the throat.

Prozac side effect: Hemorrhoids

Small rounded purplish swollen veins that either bleed, itch or are painful and appear around the anus.
Prozac side effect: Increased Stool frequency

Prozac side effect: Indigestion

Unable to properly consume and absorb food in the digestive tract causing constipation, nausea, stomach ache, gas, swollen belly, pain and general discomfort or sickness.

Prozac side effect: Nausea

Stomach irritation with a queasy sensation similar to motion sickness and a feeling that one is going to vomit.
Prozac side effect: Polyposis Gastric

Tumors that grow on stems in the lining of the stomach, which usually become cancerous.

Prozac side effect: Swallowing Difficulty

A feeling that food is stuck in the throat or upper chest area and won’t go down, making it difficult to swallow.
Prozac side effect: Toothache

Pain in a tooth above and below the gum line.

Prozac side effect: Vomiting

Involuntarily throwing up the contents of the stomach and usually getting a nauseated, sick feeling just prior to doing so.



Prozac side effect: Bruise

Damage to the skin resulting in a purple-green-yellow skin coloration that’s caused by breaking the blood vessels in the area without breaking the surface of the skin.

Prozac side effect: Anemia

A condition where the blood is no longer carrying enough oxygen, so the person looks pale and easily gets dizzy, weak and tired. More severely, a person can end up with an abnormal heart, as well as breathing and digestive difficulties. The causes of anemia are not enough protein in the red blood cells, or missing and chemically destroyed red blood cells, as well as diseased or destroyed bone marrow.

Prozac side effect: Nosebleed

Blood lost from the part of the face that has the organs of smell and is where the body takes in oxygen.

Prozac side effect: Hematoma

Broken blood vessels that cause a swelling in an area on the body.

Prozac side effect: Lymphadenopathy cervical

The lymph nodes in the neck, which are part of the body’s immune system get swollen and enlarge by reacting to the presence of a drug. The swelling is the result of the white blood cells multiplying in order to fight the invasion of the drug.


Prozac side effect: Arthralgia

Sudden sharp nerve pain in one or more joints.

Prozac side effect: Arthropathy

Having joint disease or abnormal joints.

Prozac side effect: Arthritis

Painfully inflamed and swollen joints. The reddened and swollen condition is brought on by a serious injury or shock to the body either from physical or emotional causes.

Prozac side effect: Back discomfort

Severe physical distress in the area from the neck to the pelvis along the backbone.

Prozac side effect: Bilirubin increased

Bilirubin is a waste product of the breakdown of old blood cells. Bilirubin is sent to the liver to be made water-soluble so it can be eliminated from the body through emptying the bladder. A drug can interfere with or damage this normal liver function creating liver disease.
Prozac side effect: Decreased weight

Uncontrolled and measured loss of heaviness or weight.
Prozac side effect: Gout

A severe arthritis condition that is caused by the dumping of a waste product called uric acid in the tissues and joints. It can become worse and cause the body to develop a deformity after going through stages of pain, inflammation, severe tenderness, and stiffness.

Prozac side effect: Hepatic enzymes increased

An increase in the amount of paired liver proteins that regulate liver processes causing a condition where the liver functions abnormally.

Prozac side effect: Hypercholesterolemia

Too much cholesterol in the blood stream.

Prozac side effect: Hyperglycemia

An unhealthy amount of sugar in the blood.

Prozac side effect: Increased weight

A concentration and storage of fat in the body accumulating over a period of time caused by unhealthy eating patterns, that can predispose the body to many disorders and diseases.

Prozac side effect: Jaw pain

The pain due to irritation and swelling of the nerves associated with the mouth area where it opens and closes just in front of the ear. Some of the symptoms are pain when chewing, head aches, losing your balance, stuffy ears or ringing in the ears, and teeth grinding.
Prozac side effect: Jaw stiffness

The result of squeezing and grinding the teeth while asleep that can cause your teeth to deteriorate as well as the muscles and joints of the jaw.
Prozac side effect: Joint stiffness

A loss of free motion and easy flexibility where any two bones come together.

Prozac side effect: Muscle cramp

When muscles contract uncontrollably without warning and do not relax. The muscles of any of the body’s organs can cramp.

Prozac side effect: Muscle stiffness

Tightening of muscles making it difficult to bend.

Prozac side effect: Muscle weakness

Loss of physical strength.

Prozac side effect: Myalgia

A general widespread pain and tenderness of the muscles.

Prozac side effect: Thirst

A strong, unnatural craving for moisture/water in the mouth and throat.



Prozac side effect: Asthma

A disease of the breathing system initiated by and allergic reaction or a chemical with repeated attacks of coughing, sticky mucus, wheezing, shortness of breath, and a tight feeling in the chest. The disease can reach a state where it stops a person from exhaling, leading to unconsciousness and death.

Prozac side effect: Breath, Shortness

Unnatural breathing using a lot off effort resulting in not enough air taken in by the body.

Prozac side effect: Bronchitis

Inflammation of the two main breathing tubes leading from the windpipe to the lungs. The disease is marked with coughing, a low-grade fever, chest pains, and hoarseness, caused by an allergic reaction.

Prozac side effect: Coughing

A cough is the response to an irritation, such as mucus, that causes the muscles controlling the breathing process to expel air from the lungs suddenly and noisily to keep the air passages free from the irritating material.

Prozac side effect: Laryngitis

Inflammation of the voice box characterized by hoarseness, sore throat, and coughing. It can be cause by straining the voice or exposure to infectious, allergic or chemical irritation.

Prozac side effect: Nasal congestion

The presence of an abnormal amount of fluid in the nose.

Prozac side effect: Pneumonia Tracheitis

Bacterial infection of the air passageways and lungs that causes redness, swelling and pain in the windpipe. Other symptoms are high fever, chills, pain in the chest, difficulty in breathing, and coughing with mucus discharge.

Prozac side effect: Rhinitis

Chemical irritation causing pain, redness and swelling in the mucus membranes of the nose.

Prozac side effect: Sinus congestion

The mucus-lined areas of the bones in the face that are thought to help warm and moisten air to the nose. These areas become clogged with excess fluid or infected.

Prozac side effect: Sinus headache

The abnormal amount of fluid in the hollows of the face bone area especially around the nose. This excess fluid creates pressure, causing pain in the head.

Prozac side effect: Sinusitis

The body reacting to chemical irritation causing redness, swelling and pain in the area of the hollows in the facial bones especially around the nose.


Prozac side effect: Neck or shoulder pain

Hurtful sensations of the nerve endings caused by damage to the tissues in the neck and shoulder signaling danger of disease.
Prozac side effects



Prozac side effect: Acne

Eruptions of the oils glands of the skin, especially on the face, marked by pimples, blackheads, whiteheads, bumps, and more severely, by cysts and scarring.

Prozac side effect: Alopecia

The loss of hair or baldness.
Prozac side effect: Eczema

A severe or continuing skin disease marked by redness, crusting and scaling with watery blisters and itching. It is often difficult to treat and will sometimes go away only to reappear again.

Prozac side effect: Dermatitis

Generally irritated skin that can be caused by any of a number of irritating things such as parasites, fungus, bacteria, or foreign substances causing an allergic reaction. It is a general inflammation of the skin.

Prozac side effect: Dry lips

The lack of normal moisture in the fleshy folds that surround the mouth.

Prozac side effect: Dry skin

The lack of normal moisture/oils in the surface layer of the body. The skin is the body’s largest organ.

Prozac sIde effects: Folliculitis

Inflammation of a follicle (small body sac) especially a hair follicle. A hair follicle contains the root of a hair.

Prozac side effect: Furunculosis

Skin boils that show up repeatedly.

Prozac side effect: Lipoma

A tumor of mostly fat cells that is not health endangering.

Prozac side effect: Pruritus

Extreme itching of often-undamaged skin.

Prozac side effect: Rash

A skin eruption or discoloration that may or may not be itching, tingling, burning, or painful. It may be caused by an allergy, an skin irritation, a skin disease.

Prozac side effect: Skin nodule

A bulge, knob, swelling or outgrowth in the skin that is a mass of tissue or cells.


Prozac side effect: Conjunctivitis

Infection of the membrane that covers the eyeball and lines the eyelid, caused by a virus, allergic reaction, or an irritating chemical. It is characterized by redness, a discharge of fluid and itching.

Prozac side effect: Dry eyes

Lack of moisture in the eyes.

Prozac side effect: Earache

Pain in the ear.

Prozac side effect: Eye infection

The invasion of the eye tissue by a bacteria, virus, fungus, etc, causing damage to the tissue, with toxicity. Infection spreading in the body progresses into disease.

Prozac side effect: Eye irritation

An inflammation of the eye.

Prozac side effect: Metallic taste

A range of taste impairment from distorted taste to a complete loss of taste.

Prozac side effect: Pupils dilated

Abnormal expansion of the blace circular opening in the center of the eye.

Prozac side effect: Taste alteration

Abnormal flavor detection in food.

Prozac side effect: Tinnitus

A buzzing, ringing, or whistling sound in one or both ears occurring from the internal use of certain drugs.

Prozac side effect: Vision, Abnormal

Normal images are seen differently by the viewer.

Prozac side effect: Vision, Blurred

Eyesight is dim or indistinct and hazy in outline or appearance.

Prozac side effect: Visual disturbance

Eyesight is interfered with or interrupted. Some disturbances are light sensitivity and the inability to easily distinguish colors.

Prozac side effect: Blood in urine

Blood is present when one empties liquid waste product of the kidneys through the bladder by urinating in the toilet turning the water pink to bright red. Or you could see pots of blood in the water after urinating.

Prozac side effect: Dysuria

Difficult or painful urination.

Prozac side effect: Kidney stone

Small hard masses of salt deposits that the kidney forms.

Prozac side effect: Urinary frequency

Having to urinate more often than usual or between unusually short time periods.

Prozac side effect: Urinary tract infection

An invasion of bacteria, viruses, fungi, etc., of the system in the body that starts with the kidneys and eliminates urine from the body. If the invasion goes unchecked it can injure tissue and progress into disease.

Prozac side effect: Urinary urgency

A sudden compelling urge to urinate, accompanied by discomfort in the bladder.


Prozac side effect: Anorgasmia

Failure to experience an orgasm.

Prozac side effect: Ejaculation disorder

Dysfunction of the discharge of semen during orgasm.

Prozac side effect: Menstrual disorder

Dysfunction of the discharge during the monthly menstrual cycle.

Prozac side effect: Acute renal failure

The kidneys stop functioning properly to excrete wastes.
Prozac side effect: Angioedema

Intensely itching and swelling welts on the skin called hives caused by an allergic reaction to internal or external agents. The reaction is common to a food or a drug. Chronic cases can last for a long period of time.
Prozac side effect: Toxic epidermal necrolysis

An abnormal condition where a large portion of skin becomes intensely red and peels off like a second-degree burn. Often the symptoms include blistering.

Prozac side effect: Gastrointestinal hemorrhage

Stomach and intestinal excessive internal bleeding.

Prozac side effect: Grand Mal seizures (or convulsions)

A recurring sudden violent and involuntary attack of muscle spasms with a loss of consciousness.
Prozac side effects: Neuroleptic malignant syndrome

A life threatening, rare reaction to an anti-psychotic drug marked by fever, muscular rigidity, changed mental status, and dysfunction of the autonomic nervous system.

Prozac side effect: Pancreatitis

Chemical irritation with redness, swelling, and pain in the pancreas where digestive enzymes and hormones are secreted.

Prozac side effect: QT prolongation

A very fast heart rhythm disturbance that is too fast for the heart to beat effectively so the blood to the brain falls causing a sudden loss of consciousness and may cause sudden cardiac death.

Prozac side effect: Rhabdomyolysis

The breakdown of muscle fibers that releases the fibers into the circulatory system. Some of the fibers are poisonous to the kidney and frequently result in kidney damage.
Prozac side effect: Serotonin syndrome

A disorder brought on by excessive levels of serotonin caused by drugs and can be fatal as death from this side effect can come very rapidly.
Prozac side effect: Thrombocytopenia

An abnormal decrease in the number of blood platelets in the circulatory system. A decrease in platelets would cause a decrease in the ability of the blood to clot when necessary.
Prozac side effect: Torsades de Pointes

Unusual rapid heart rhythm starting in the lower heart chambers. If the short bursts of rapid heart rhythm continue for a prolonged period it can degenerate into a more rapid rhythm and can be fatal.


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Eur J Drug Metab Pharmacokinet. 2009 Jan-Mar;34(1):19-26.

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New light on the serotonergic paradox in the rat circadian system.Cuesta M, Clesse D, Pévet P, Challet E.
J Neurochem. 2009 Apr 27. [Epub ahead of print]

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High resolution micro-SPECT scanning in rats using (125)I beta-CIT: Effects of chronic treatment with carbamazepine.
Cain SM, Ruest T, Pimlott S, Patterson J, Duncan R, Dewar D, Sills GJ.
Epilepsia. 2009 May 9. [Epub ahead of print]

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Mirtazapine: a review of its use in major depression and other psychiatric disorders.
Croom KF, Perry CM, Plosker GL.
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Utility of atypical antipsychotics in the treatment of resistant unipolar depression.
Debattista C, Hawkins J.
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Efficacy and safety of selective serotonin re-uptake inhibitors in the treatment of premature ejaculation: a systematic evaluation
Huang XK, Lu YP, Luo SW, Wang F, Xie ZY, Wang XD.
Zhonghua Nan Ke Xue. 2009 Mar;15(3):248-55. Chinese.

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Placental transfer of SSRI and SNRI antidepressants and effects on the neonate.
Rampono J, Simmer K, Ilett KF, Hackett LP, Doherty DA, Elliot R, Kok CH, Coenen A, Forman T.
Pharmacopsychiatry. 2009 May;42(3):95-100. Epub 2009 May 18.

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Potentially inappropriate medication prescribing in outpatient practices: Prevalence and patient characteristics based on electronic health records.
Buck MD, Atreja A, Brunker CP, Jain A, Suh TT, Palmer RM, Dorr DA, Harris CM, Wilcox AB.
Am J Geriatr Pharmacother. 2009 Apr;7(2):84-92.

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Behavioral abnormality and pharmacologic response in social isolation-reared mice.
Koike H, Ibi D, Mizoguchi H, Nagai T, Nitta A, Takuma K, Nabeshima T, Yoneda Y, Yamada K.
Behav Brain Res. 2009 Aug 24;202(1):114-21. Epub 2009 Mar 31.

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Depression in children and adolescents.
Hazell P.
Clin Evid (Online). 2009 Jan 7;2009. pii: 1008.

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Pediatric generalized anxiety disorder: epidemiology, diagnosis, and management.
Keeton CP, Kolos AC, Walkup JT.
Paediatr Drugs. 2009;11(3):171-83. doi: 10.2165/00148581-200911030-00003.

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Effects of chronic fluoxetine treatment on catalepsy and immune response in mice genetically predisposed to freezing reaction: the role of 5-HT1A and 5-HT2A receptors and tph2 and SERT genes
[No authors listed]
Zh Vyssh Nerv Deiat Im I P Pavlova. 2009 Mar-Apr;59(2):237-44. Russian.

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Fluoxetine treatment affects nitrogen waste excretion and osmoregulation in a marine teleost fish.
Morando MB, Medeiros LR, McDonald MD.
Aquat Toxicol. 2009 Apr 18. [Epub ahead of print]

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Binding of CYP2C9 with diverse drugs and its implications for metabolic mechanism.
Wang JF, Yan JY, Wei DQ, Chou KC.
Med Chem. 2009 May;5(3):263-70.

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Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today.
López-Muñoz F, Alamo C.
Curr Pharm Des. 2009;15(14):1563-86.

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Application of liquid chromatography coupled with mass spectrometry (LC/MS) to determine antidepressants in blood samples
Pufal E, Sykutera M.
Arch Med Sadowej Kryminol. 2009 Oct-Dec;58(4):171-6. Polish.

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Antipsychotics in clinical practice. Treatment of the first schizophrenic episode
Jarema M, Meder J, Araszkiewicz A, Tyszkowska M.
Psychiatr Pol. 2008 Nov-Dec;42(6):841-58. Polish.

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Paradoxical Anxiogenic Response of Juvenile Mice to Fluoxetine.
Oh JE, Zupan B, Gross S, Toth M.
Neuropsychopharmacology. 2009 May 13. [Epub ahead of print]

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Trismus induced by fluoxetine.
Filho AS, Carvalho DL, Tumas V, Hetem LA, Ferrari MC, Crippa JA.
J Clin Psychopharmacol. 2009 Jun;29(3):306-7. No abstract available.

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Treatment-emergent sexual dysfunction related to antidepressants: a meta-analysis.
Serretti A, Chiesa A.
J Clin Psychopharmacol. 2009 Jun;29(3):259-66.

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Ascorbic acid administration produces an antidepressant-like effect: evidence for the involvement of monoaminergic neurotransmission.
Binfaré RW, Rosa AO, Lobato KR, Santos AR, Rodrigues AL.
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Early raise of BDNF in hippocampus suggests induction of posttranscriptional mechanisms by antidepressants.
Musazzi L, Cattaneo A, Tardito D, Barbon A, Gennarelli M, Barlati S, Racagni G, Popoli M.
BMC Neurosci. 2009 May 13;10(1):48. [Epub ahead of print]

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5-HT1A receptor antagonism reverses and prevents fluoxetine-induced sexual dysfunction in rats.
Sukoff Rizzo SJ, Pulicicchio C, Malberg JE, Andree TH, Stack GP, Hughes ZA, Schechter LE, Rosenzweig-Lipson S.
Int J Neuropsychopharmacol. 2009 May 13:1-9. [Epub ahead of print]

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Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures.
Zhou Z, Zhen J, Karpowich NK, Law CJ, Reith ME, Wang DN.
Nat Struct Mol Biol. 2009 May 10. [Epub ahead of print]

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Effects of chronic fluoxetine treatment on the rat somatosensory cortex: activation and induction of neuronal structural plasticity.
Guirado R, Varea E, Castillo-Gómez E, Gómez-Climent MA, Rovira-Esteban L, Blasco-Ibáñez JM, Crespo C, Martínez-Guijarro FJ, Nàcher J.
Neurosci Lett. 2009 Jun 19;457(1):12-5. Epub 2009 Apr 5.

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Inhibitory effect of selective serotonin reuptake inhibitors on the vesicular monoamine transporter 2.
Yasumoto S, Tamura K, Karasawa J, Hasegawa R, Ikeda K, Yamamoto T, Yamamoto H.
Neurosci Lett. 2009 May 1;454(3):229-32. Epub 2009 Mar 18.

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Quantitative evaluation of serotonin release and clearance in Drosophila.
Borue X, Cooper S, Hirsh J, Condron B, Venton BJ.
J Neurosci Methods. 2009 May 15;179(2):300-8. Epub 2009 Mar 4.

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Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus.
Jin Y, Lim CM, Kim SW, Park JY, Seo JS, Han PL, Yoon SH, Lee JK.
Brain Res. 2009 May 7. [Epub ahead of print]

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Serotonin stimulates platelet receptor shedding by tumor necrosis factor-alpha-converting enzyme (ADAM17).
Duerschmied D, Canault M, Lievens D, Brill A, Cifuni SM, Bader M, Wagner DD.
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Psychopharmacology (Berl). 2009 May 7. [Epub ahead of print]

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Pariente A, Daveluy A, Laribière-Bénard A, Miremont-Salame G, Begaud B, Moore N.
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Schmauß M, Messer T.
Fortschr Neurol Psychiatr. 2009 May 4. [Epub ahead of print] German.

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Busch SH, Barry CL.
Health Aff (Millwood). 2009 May-Jun;28(3):724-33.

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Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment response.
Licinio J, Dong C, Wong ML.
Arch Gen Psychiatry. 2009 May;66(5):488-97.

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Cifani C, Zanoncelli A, Tessari M, Righetti C, Di Francesco C, Ciccocioppo R, Massi M, Melotto S.
Addict Biol. 2009 Apr 28. [Epub ahead of print]

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Lowry CA, Hale MW, Burke KA, Renner KJ, Moore FL.
Horm Behav. 2009 Jun;56(1):177-184. Epub 2009 May 3.

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Berman RM, Fava M, Thase ME, Trivedi MH, Swanink R, McQuade RD, Carson WH, Adson D, Taylor L, Hazel J, Marcus RN.
CNS Spectr. 2009 Apr;14(4):197-206.

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Antidepressants at Environmentally Relevant Concentrations Affect Predator Avoidance Behavior of Larval Fathead Minnows (Pimephales promelas).
Painter MM, Buerkley MA, Julius ML, Vajda AM, Norris DO, Barber LB, Furlong ET, Schultz MM, Schoenfuss HL.
Environ Toxicol Chem. 2009 Apr 30:1. [Epub ahead of print]

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Early induction of CREB activation and CREB-regulating signalling by antidepressants.
Tardito D, Musazzi L, Tiraboschi E, Mallei A, Racagni G, Popoli M.
Int J Neuropsychopharmacol. 2009 Apr 29:1-15. [Epub ahead of print]

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Cullen K, Klimes-Dougan B, Kumra S.
Minn Med. 2009 Mar;92(3):45-8.

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Orosomucoid influences the response to antidepressants in major depressive disorder.
Harley J, Roberts R, Joyce P, Mulder R, Luty S, Frampton C, Kennedy M.
J Psychopharmacol. 2009 Apr 24. [Epub ahead of print]

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Pharmaceutical and personal care products in tile drainage following surface spreading and injection of dewatered municipal biosolids to an agricultural field.
Edwards M, Topp E, Metcalfe CD, Li H, Gottschall N, Bolton P, Curnoe W, Payne M, Beck A, Kleywegt S, Lapen DR.
Sci Total Environ. 2009 Jul 1;407(14):4220-30. Epub 2009 Apr 26.

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Results of a retrospective claims database analysis of differences in antidepressant treatment persistence associated with escitalopram and other selective serotonin reuptake inhibitors in the United States.Esposito D, Wahl P, Daniel G, Stoto MA, Erder MH, Croghan TW.
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Inhibitory effect of antidepressants on the NMDA-evoked [(3)H]noradrenaline release from rat hippocampal slices.
Mayer A, Szasz BK, Kiss JP.
Neurochem Int. 2009 Apr 22. [Epub ahead of print]

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Duan DM, Tu Y, Chen LP, Wu ZJ.
Zhongguo Zhen Jiu. 2009 Feb;29(2):139-44. Chinese.

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Coccaro EF, Lee RJ, Kavoussi RJ.
J Clin Psychiatry. 2009 Apr 21. [Epub ahead of print]

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Neonatal fluoxetine exposure affects the neuronal structure in the somatosensory cortex and somatosensory-related behaviors in adolescent rats.
Lee LJ.
Neurotox Res. 2009 Apr;15(3):212-23. Epub 2009 Mar 4.

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Sloot WN, Bowden HC, Yih TD.
Reprod Toxicol. 2009 Apr 19. [Epub ahead of print]

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Fontenot MB, Musso MW, McFatter RM, Anderson GM.
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Allostatic tumor-burden induces depression-associated changes in hepatoma-bearing mice.
Qi H, Ma J, Liu YM, Yang L, Peng L, Wang H, Chen HZ.
J Neurooncol. 2009 Apr 21. [Epub ahead of print]

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Food restriction and streptozotocin differentially modify sensitivity to the hypothermic effects of direct- and indirect-acting serotonin receptor agonists in rats.
Li JX, Koek W, France CP.
Eur J Pharmacol. 2009 Jun 24;613(1-3):60-63. Epub 2009 Apr 18.

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Rephaeli A, Gil-Ad I, Aharoni A, Tarasenko I, Tarasenko N, Geffen Y, Halbfinger E, Nisemblat Y, Weizman A, Nudelman A.
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Jones JD, Hall FS, Uhl GR, Rice K, Riley AL.
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Mazza M, Mazza O, Pomponi M, Di Nicola M, Padua L, Vicini M, Bria P, Mazza S.
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Vitiello B.
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Küçükibrahimo?lu E, Sayg?n MZ, Cal??kan M, Kaplan OK, Unsal C, Gören MZ.
Eur J Clin Pharmacol. 2009 Apr 17. [Epub ahead of print]

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Murakami S, Matsuura M, Satou T, Hayashi S, Koike K.
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Escitalopram versus other antidepressive agents for depression.
Cipriani A, Santilli C, Furukawa TA, Signoretti A, Nakagawa A, McGuire H, Churchill R, Barbui C.
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Cipriani A, La Ferla T, Furukawa TA, Signoretti A, Nakagawa A, Churchill R, McGuire H, Barbui C.
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Brown J, O'Brien PM, Marjoribanks J, Wyatt K.
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Choi YJ.
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Ferreira-E-Silva WT, Galvão BA, Ferraz-Pereira KN, de-Castro CB, Manhães-de-Castro R.
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Chronic psychotropic drug treatment causes differential expression of Reelin signaling system in frontal cortex of rats.
Fatemi SH, Reutiman TJ, Folsom TD.
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Baughman KR, Bourguet CC, Ober SK.
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Schwarz AJ, Gozzi A, Bifone A.
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Serotonin, social status and sex change in the bluebanded goby Lythrypnus dalli.
Lorenzi V, Carpenter RE, Summers CH, Earley RL, Grober MS.
Physiol Behav. 2009 Jun 22;97(3-4):476-83. Epub 2009 Apr 2.

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Fluoxetine affects weight gain and expression of feeding peptides in the female goldfish brain.
Mennigen JA, Harris EA, Chang JP, Moon TW, Trudeau VL.
Regul Pept. 2009 Jan 21. [Epub ahead of print]

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Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression.
Berrocoso E, Mico JA.
Int J Neuropsychopharmacol. 2009 Apr 3:1-12. [Epub ahead of print]

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Loprinzi CL, Sloan J, Stearns V, Slack R, Iyengar M, Diekmann B, Kimmick G, Lovato J, Gordon P, Pandya K, Guttuso T Jr, Barton D, Novotny P.
J Clin Oncol. 2009 Mar 30. [Epub ahead of print]

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Quantitative changes in hippocampal microvasculature of chronically stressed rats: No effect of fluoxetine treatment.
Czéh B, Abumaria N, Rygula R, Fuchs E.
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Morishita S.
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The SNRI venlafaxine improves emotional unawareness in patients with post-stroke depression.
Cravello L, Caltagirone C, Spalletta G.
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Teratogenesis associated with antibipolar agents.
Nguyen HT, Sharma V, McIntyre RS.
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Nicoli R, Curcio R, Rudaz S, Veuthey JL.
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Predominant previous polarity as an outcome predictor in a controlled treatment trial for depression in bipolar I disorder patients.
Vieta E, Berk M, Wang W, Colom F, Tohen M, Baldessarini RJ.
J Affect Disord. 2009 Mar 24. [Epub ahead of print]

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Double-blind placebo-controlled trial of fluoxetine in adolescents with comorbid major depression and an alcohol use disorder.
Cornelius JR, Bukstein OG, Wood DS, Kirisci L, Douaihy A, Clark DB.
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Engin E, Treit D, Dickson CT.
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Incidence of major malformations in infants following antidepressant exposure in pregnancy: results of a large prospective cohort study.Einarson A, Choi J, Einarson TR, Koren G.
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Ramirez AJ, Brain RA, Usenko S, Mottaleb MA, O'Donnell JG, Stahl LL, Wathen JB, Snyder BD, Pitt JL, Perez-Hurtado P, Dobbins LL, Brooks BW, Chambliss CK.
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Galecki P, Szemraj J, Bielkiewicz M, Zboralski K, Galecka E.
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Trivedi MH, Corey-Lisle PK, Guo Z, Lennox RD, Pikalov A, Kim E.
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Baseline severity of depression predicts antidepressant drug response relative to escitalopram.
Kilts CD, Wade AG, Andersen HF, Schlaepfer TE.
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Guilluy C, Eddahibi S, Agard C, Guignabert C, Izikki M, Tu L, Savale L, Humbert M, Fadel E, Adnot S, Loirand G, Pacaud P.
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alpha(2)-Adrenoceptors mediate the acute inhibitory effect of fluoxetine on locus coeruleus noradrenergic neurons.
Miguelez C, Fernandez-Aedo I, Torrecilla M, Grandoso L, Ugedo L.
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